The Atypical Antipsychotic Lurasidone Affects Brain but Not Liver Cytochrome P450 2D (CYP2D) Activity. A Comparison with Other Novel Neuroleptics and Significance for Drug Treatment of Schizophrenia

The aim of this work was to study the effect of prolonged lurasidone administration on the cytochrome 2D (CYP2D) expression and activity in the rat liver and selected brain structures involved in the therapeutic or side effects of this neuroleptic. Male Wistar rats received lurasidone (1 mg/kg ip.)...

詳細記述

書誌詳細
出版年:Cells
主要な著者: Przemysław J. Danek, Władysława A. Daniel
フォーマット: 論文
言語:英語
出版事項: MDPI AG 2022-11-01
主題:
オンライン・アクセス:https://www.mdpi.com/2073-4409/11/21/3513