Direct comparisons of neural activity during placebo analgesia and nocebo hyperalgesia between humans and rats

Abstract Placebo analgesia and nocebo hyperalgesia can profoundly alter pain perception, offering critical implications for pain management. While animal models are increasingly used to explore the underlying mechanisms of these phenomena, it remains unclear whether animals experience placebo and no...

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Bibliographic Details
Published in:Communications Biology
Main Authors: Damien C. Boorman, Lewis S. Crawford, Luke A. Henderson, Kevin A. Keay
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Online Access:https://doi.org/10.1038/s42003-025-07993-1