A phase 2a study investigating the effects of ritlecitinib on brainstem auditory evoked potentials and intraepidermal nerve fiber histology in adults with alopecia areata

Abstract Reversible axonal swelling and brainstem auditory evoked potential (BAEP) changes were observed in standard chronic (9‐month) toxicology studies in dogs treated with ritlecitinib, an oral Janus kinase 3/tyrosine kinase expressed in hepatocellular carcinoma family kinase inhibitor, at exposu...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Pharmacology Research & Perspectives
المؤلفون الرئيسيون: Samira Anderson, Guido Cavaletti, Linda J. Hood, Michael Polydefkis, David N. Herrmann, Gary Rance, Brett King, Amy J. McMichael, Maryanne M. Senna, Brian S. Kim, Lynne Napatalung, Robert Wolk, Samuel H. Zwillich, Gregor Schaefer, Yankun Gong, Melanie Sisson, Holly B. Posner
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Wiley 2024-08-01
الموضوعات:
alopecia areata
audiological
axonal dystrophy
BAEP
brainstem auditory evoked potentials
intraepidermal nerve fibers
الوصول للمادة أونلاين:https://doi.org/10.1002/prp2.1204

الانترنت

https://doi.org/10.1002/prp2.1204

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