Emerging horizons: clinical applications and multifaceted benefits of SGLT-2 inhibitors beyond diabetes

SGLT-2 inhibitors, initially developed for type 2 diabetes, demonstrate profound cardiorenal and metabolic benefits. This review synthesizes evidence from clinical trials and mechanistic studies to elucidate their roles in cardiovascular diseases, chronic kidney disease, and non-alcoholic fatty live...

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Bibliographic Details

Published in:	Frontiers in Cardiovascular Medicine
Main Authors:	Qing Feng, Miaoqiong Wu, Zizhao Mai
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-03-01
Subjects:	SGLT-2 inhibitors cardiovascular diseases heart failure chronic kidney disease nonalcoholic fatty liver disease
Online Access:	https://www.frontiersin.org/articles/10.3389/fcvm.2025.1482918/full