Mycoplasma genitalium Protein of Adhesion Suppresses T Cell Activation via CypA-CaN-NFAT Pathway

ABSTRACT Mycoplasma genitalium is a prokaryotic microorganism that causes urogenital tract infections. M. genitalium protein of adhesion (MgPa) was essential for M. genitalium attachment and subsequent invasion into host cells. Our prior research confirmed that Cyclophilin A (CypA) was the binding r...

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Bibliographic Details

Published in:	Microbiology Spectrum
Main Authors:	Dan Luo, Haodang Luo, Xiaoliang Yan, Aihua Lei, Jun He, Yating Liao, Kailan Peng, Xia Li, Youyuan Ye, Li Chen, Zhuo Zeng, Hua Xiao, Yanhua Zeng
Format:	Article
Language:	English
Published:	American Society for Microbiology 2023-06-01
Subjects:	CaN-NFAT signaling M. genitalium protein of adhesion T cell activation cyclophilin A
Online Access:	https://journals.asm.org/doi/10.1128/spectrum.04503-22