Inhibitors of Rho/MRTF/SRF Transcription Pathway Regulate Mitochondrial Function

RhoA-regulated gene transcription by serum response factor (SRF) and its transcriptional cofactor myocardin-related transcription factors (MRTFs) signaling pathway has emerged as a promising therapeutic target for pharmacological intervention in multiple diseases. Altered mitochondrial metabolism is...

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Bibliographic Details

Published in:	Cells
Main Authors:	Pankaj Patyal, Xiaomin Zhang, Ambika Verma, Gohar Azhar, Jeanne Y. Wei
Format:	Article
Language:	English
Published:	MDPI AG 2024-02-01
Subjects:	Rho/MRTF/SRF mitochondria bioenergetics histone-4 acetylation oxidative stress
Online Access:	https://www.mdpi.com/2073-4409/13/5/392