The New Era of Cancer Immunotherapy: Targeting Myeloid-Derived Suppressor Cells to Overcome Immune Evasion

Suppression of antitumor immune responses is one of the main mechanisms by which tumor cells escape from destruction by the immune system. Myeloid-derived suppressor cells (MDSCs) represent the main immunosuppressive cells present in the tumor microenvironment (TME) that sustain cancer progression....

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Paola De Cicco, Giuseppe Ercolano, Angela Ianaro
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-07-01
Subjects:	immune evasion melanoma breast cancer hepatocellular cacinoma non-small cell lung cancer (NSCLC) myeloid derived suppressor cell (MDSC)
Online Access:	https://www.frontiersin.org/article/10.3389/fimmu.2020.01680/full