Role of ACTH in the interactive/paracrine regulation of adrenal steroid secretion in physiological and pathophysiological conditions

In the normal human adrenal gland, steroid secretion is regulated by a complex network of autocrine/paracrine interactions involving bioactive signals released by endothelial cells, nerve terminals, chromaffin cells, immunocompetent cells and adrenocortical cells themselves. ACTH can be locally prod...

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Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Herve Lefebvre, Michael Thomas, Céline DUPARC, Jerome Bertherat, Estelle Louiset
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-07-01
Subjects:	Hyperplasia ACTH VEGF endothelial cell biology cortisol levels Cushing’s syndrome
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fendo.2016.00098/full