Spectrochemical, medicinal, and toxicological studies of ketoprofen and its newly designed analogs; quantum chemical, and drug discovery approach

Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used as analgesics, antipyretics, anti-clotting, and anti-inflammatory agents. One such NSAID, ketoprofen (KTP), is prescribed to treat pain, sprains, menstrual irregularities, osteoarthritis (OA), and rheumatoid arthritis (RA). By inhibitin...

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Bibliographic Details

Published in:	Informatics in Medicine Unlocked
Main Authors:	Mst. Farhana Afrin, Emranul Kabir, M.R.O. Khan Noyon, Md Mosharef H. Bhuiyan, Mst Sharmin Sultana Shimu, Md Jahangir Alam, Monir Uzzaman, Md Walid Hossain Talukder
Format:	Article
Language:	English
Published:	Elsevier 2023-01-01
Subjects:	Ketoprofen Cyclooxygenase Molecular docking and dynamics simulation Nonbonded interactions ADMET and PASS prediction
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352914823002459