Evolving role of myocardial fibrosis in heart failure with preserved ejection fraction

Heart failure with preserved ejection fraction (HFpEF) is a complex clinical diagnosis with a heterogeneous pathophysiology and clinical presentation. The hallmark of HFpEF is diastolic dysfunction associated with left ventricular remodeling and fibrosis. Myocardial interstitial fibrosis (MIF) occur...

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Bibliographic Details

Published in:	Frontiers in Cardiovascular Medicine
Main Authors:	Muhammad K. Malik, Menhel Kinno, Max Liebo, Mingxi D. Yu, Mushabbar Syed
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Subjects:	heart failure with preserved ejection myocardial fibrosis inflammation biomarkers collagen metabolism
Online Access:	https://www.frontiersin.org/articles/10.3389/fcvm.2025.1573346/full