Emerging roles of HECT‐type E3 ubiquitin ligases in autophagy regulation

Autophagy is a conserved self‐eating process that delivers cytoplasmic material to the lysosome to allow degradation of intracellular components, including soluble, unfolded and aggregated proteins, damaged organelles, and invading microorganisms. Autophagy provides a homeostatic control mechanism a...

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Bibliographic Details

Published in:	Molecular Oncology
Main Authors:	Gerry Melino, Francesco Cecconi, Pier Giuseppe Pelicci, Tak Wah Mak, Francesca Bernassola
Format:	Article
Language:	English
Published:	Wiley 2019-10-01
Subjects:	autophagy HECT E3 ubiquitin ligases proteasomal degradation ubiquitylation
Online Access:	https://doi.org/10.1002/1878-0261.12567