Puerarin ameliorates high glucose-induced MIN6 cell injury by activating PINK1/Parkin-mediated mitochondrial autophagy

The dysfunction of pancreatic β-cells plays a pivotal role in the pathogenesis of type 2 diabetes mellitus (T2DM). Despite numerous studies demonstrating the anti-inflammatory and antioxidant properties of puerarin, the protective effects of puerarin on β-cells remain poorly understood. Hence, this...

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Bibliographic Details

Published in:	Heliyon
Main Authors:	Hongyang Zhu, You Yu, Yuting Li, Shiyao Chang, Yuhui Liu
Format:	Article
Language:	English
Published:	Elsevier 2024-08-01
Subjects:	Type 2 diabetes β-cell dysfunction Puerarin Mitochondrial autophagy Mitochondrial apoptosis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844024122074