Single-injection hyaluronic acid treatment demonstrates non-inferiority in the relief of symptomatic knee osteoarthritis: A randomized double-blind, multi-center controlled study

Objective: To compare two sodium hyaluronate formulations (HYMOVIS® ONE and MONOVISC®) for single intra-articular (IA) injection in patients with knee osteoarthritis pain. Methods: This randomized, controlled study included 347 subjects allocated to two treatment arms: HYMOVIS® ONE (n = 175) and MON...

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Bibliographic Details

Published in:	Osteoarthritis and Cartilage Open
Main Authors:	C. Ruosi, U.G. Longo, N. Giordan, L. Saracino, M.A. Minetto, C. Busso, N. Migliaccio, C. Melchior, A. Guardoli, E. Vaienti, G. Scita, F. Atzori, G. Chitoni, N. Orabona, F. Benazzo
Format:	Article
Language:	English
Published:	Elsevier 2026-06-01
Subjects:	Osteoarthritis Knee Hyaluronic acid
Online Access:	http://www.sciencedirect.com/science/article/pii/S2665913126000105