Bioengineered 3D human kidney tissue, a platform for the determination of nephrotoxicity.

The staggering cost of bringing a drug to market coupled with the extremely high failure rate of prospective compounds in early phase clinical trials due to unexpected human toxicity makes it imperative that more relevant human models be developed to better predict drug toxicity. Drug-induced nephro...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Teresa M DesRochers, Laura Suter, Adrian Roth, David L Kaplan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Online Access:http://europepmc.org/articles/PMC3597621?pdf=render