Exploring chronic and transient tumor hypoxia for predicting the efficacy of hypoxia-activated pro-drugs

Abstract Hypoxia, a low level of oxygen in the tissue, arises due to an imbalance between the vascular oxygen supply and oxygen demand by the surrounding cells. Typically, hypoxia is viewed as a negative marker of patients’ survival, because of its implication in the development of aggressive tumors...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:npj Systems Biology and Applications
المؤلفون الرئيسيون: Shreya Mathur, Shannon Chen, Katarzyna A. Rejniak
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Nature Portfolio 2024-01-01
الوصول للمادة أونلاين:https://doi.org/10.1038/s41540-023-00327-z