Therapeutic effects of orexin-A in sepsis-associated encephalopathy in mice

Abstract Background Sepsis-associated encephalopathy (SAE) causes acute and long-term cognitive deficits. However, information on the prevention and treatment of cognitive dysfunction after sepsis is limited. The neuropeptide orexin-A (OXA) has been shown to play a protective role against neurologic...

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Bibliographic Details

Published in:	Journal of Neuroinflammation
Main Authors:	Jing Guo, Zhuo Kong, Sha Yang, Jingjing Da, Liangzhao Chu, Guoqiang Han, Jian Liu, Ying Tan, Jiqin Zhang
Format:	Article
Language:	English
Published:	BMC 2024-05-01
Subjects:	Orexin-A Sepsis-associated encephalopathy Inflammation Cognitive dysfunction Orexin receptors
Online Access:	https://doi.org/10.1186/s12974-024-03111-w