Thermoreversible hyaluronan-hydrogel and autologous nucleus pulposus cell delivery regenerates human intervertebral discs in an ex vivo, physiological organ culture model

Numerous studies show promise for cell-based tissue engineering strategies aiming to repair painful intervertebral disc (IVD) degeneration. However, clinical translation to human IVD repair is slow. In the present study, the regenerative potential of an autologous nucleus pulposus (NP)-cell-seeded t...

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Bibliographic Details

Published in:	European Cells & Materials
Main Authors:	DH Rosenzweig, R Fairag, AP Mathieu, L Li, , ,, ,, D Eglin, M D’Este, T Steffen, MH Weber, JA Ouellet, L Haglund
Format:	Article
Language:	English
Published:	Forum Multimedia Publishing LLC 2018-10-01
Subjects:	Hydrogel T1ρ magnetic resonance imaging human intervertebral disc bioreactors tissue engineering nucleus pulposus autologous cell implantation.
Online Access:	http://www.ecmjournal.org/papers/vol036/pdf/v036a15.pdf