Targeting Liver <i>Xor</i> by GalNAc-siRNA Is an Effective Strategy for Hyperuricemia Therapy

Hyperuricemia, i.e., increased plasma uric acid concentration, is a common problem in clinical practice, leading to gout or nephrolithiasis, and is associated with other disorders, such as metabolic syndrome, cardiovascular disease, and chronic renal disease. Xanthine oxidoreductase (XOR) is a criti...

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出版年:	Pharmaceutics
主要な著者:	Huiyan Sun, Xinxia Wang, Yongqiang Li, Yingzhi Shen, Lin Zhang, Yingjie Xu, Junling Liu, Xuemei Fan
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2024-07-01
主題:	hyperuricemia GalNAc-siRNA xanthine oxidoreductase
オンライン･アクセス:	https://www.mdpi.com/1999-4923/16/7/938