microRNA-181c-5p stimulates the development of coronary artery disease by targeting SIRT1

Objective: MicroRNA (miR) therapeutics is a promising approach to manage coronary artery disease (CAD). Herein, this research was aimed to explore miR-181c-5p-related mechanisms in CAD through regulating SIRT1. Methods: A CAD mouse model was established by feeding a high-fat diet in 8-week-old ApoE−...

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Bibliographic Details
Published in:Hellenic Journal of Cardiology
Main Authors: Cao Ma, Xiaohui Zheng, Xiaoguang Wu, Jing Cheng, Kai Zhang
Format: Article
Language:English
Published: Elsevier 2023-01-01
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1109966622001488