Function and Dynamics of Tetraspanins during Antigen Recognition and Immunological Synapse Formation

Tetraspanin-enriched microdomains (TEMs) are specialized membrane platforms driven by protein-protein interactions that integrate membrane receptors and adhesion molecules. Tetraspanins participate in antigen recognition and presentation by antigen presenting cells (APCs) through the organization of...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Vera eRocha-Perugini, Francisco eSanchez-Madrid, Gloria eMartinez del Hoyo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-01-01
Subjects:	Antigen Presentation Tetraspanins Adhesion molecules Immunological Synapse T cell activation Tetraspanin-enriched microdomains
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00653/full