Beyond αβ T cells: NK, iNKT, and γδT cell biology in leukemic patients and potential for off-the-shelf adoptive cell therapies for AML

Acute myeloid leukemia (AML) remains an elusive disease to treat, let alone cure, even after highly intensive therapies such as stem cell transplants. Adoptive cell therapeutic strategies based on conventional alpha beta (αβ)T cells are an active area of research in myeloid neoplasms given their rem...

Full description

Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Andrew Kent, Lyndsey S. Crump, Eduardo Davila
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-08-01
Subjects:	NK cell iNKT cell gdT cell adoptive cell therapy acute myeloid leukemia immune cell engineering
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1202950/full