Unlocking nerve regeneration: electrical stimulation and bioscaffolds to enhance peripheral nerve regeneration

Peripheral nerve injury (PNI) is a challenging clinical problem resulting in disabling sensorimotor deficits, which may become permanent if recovery does not take place in a timely manner. In this review, we examine recent insights into key molecular mechanisms—particularly MAPK/ERK and PI3K/Akt—tha...

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Bibliographic Details

Published in:	Frontiers in Neuroscience
Main Authors:	Vanshit Thakkar, Melod Mehdipour, Stephano Chang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Subjects:	peripheral nerve injury nerve regeneration peripheral nerve regeneration/repair Schwann cell reprogramming electrical stimulation natural and synthetic scaffolds
Online Access:	https://www.frontiersin.org/articles/10.3389/fnins.2025.1594435/full