IVIVC Assessment of Two Mouse Brain Endothelial Cell Models for Drug Screening

Since most preclinical drug permeability assays across the blood-brain barrier (BBB) are still evaluated in rodents, we compared an in vitro mouse primary endothelial cell model to the mouse b.End3 and the acellular parallel artificial membrane permeability assay (PAMPA) models for drug screening pu...

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發表在:	Pharmaceutics
Main Authors:	Ina Puscas, Florian Bernard-Patrzynski, Martin Jutras, Marc-André Lécuyer, Lyne Bourbonnière, Alexandre Prat, Grégoire Leclair, V. Gaëlle Roullin
格式:	Article
語言:	英语
出版:	MDPI AG 2019-11-01
主題:	mouse brain microvascular endothelial cells primary cell culture bend.3 cell line ivivc blood-brain barrier
在線閱讀:	https://www.mdpi.com/1999-4923/11/11/587