Benznidazole levels in blood vary with age in rats
Benznidazole (Bz) exhibits toxic side effects in animal studies and clinical use. Reductive metabolism of Bz in liver microsomes modulates the duration of its chemotherapeutic effect and its toxicity. The rate of this metabolism depends on age and is less intense in newborns and youngsters than in a...
| 發表在: | Memorias do Instituto Oswaldo Cruz |
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| Main Authors: | , , |
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
Fundação Oswaldo Cruz (FIOCRUZ)
2011-05-01
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| 主題: | |
| 在線閱讀: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000300021&lng=en&tlng=en |