Genetic influence of the brain imaging phenotypes, brain and cerebrospinal fluid metabolites and brain genes on migraine subtypes: a Mendelian randomization and multi-omics study

Abstract Background Migraine is a complex neurological disorder with high prevalence but unclear pathogenesis. Numerous studies have suggested that migraine is associated with alterations in brain imaging phenotypes (BIPs) and dysregulation of cerebrospinal fluid (CSF) and brain metabolism; however,...

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Bibliographic Details

Published in:	The Journal of Headache and Pain
Main Authors:	Ping-An Zhang, Jie-Lin Wang, Mei-Hua Dong, Xiang-Chun Huang, Nai-Jian Li, Run-Dong Qin, Jing Li
Format:	Article
Language:	English
Published:	BMC 2025-05-01
Subjects:	Migraine Brain imaging phenotypes Brain and cerebrospinal fluid metabolites Mendelian randomization Genome-wide association Multi-omics
Online Access:	https://doi.org/10.1186/s10194-025-02063-7