Hematopoietic progenitor kinase 1 inhibits the development and progression of pancreatic intraepithelial neoplasia

Ras plays an essential role in the development of acinar-to-ductal metaplasia (ADM) and pancreatic ductal adenocarcinoma (PDAC). However, mutant Kras is an inefficient driver for PDAC development. The mechanisms of the switching from low Ras activity to high Ras activity that are required for develo...

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التفاصيل البيبلوغرافية

الحاوية / القاعدة:	The Journal of Clinical Investigation
المؤلفون الرئيسيون:	Hua Wang, Rohan Moniruzzaman, Lei Li, Baoan Ji, Yi Liu, Xiangsheng Zuo, Reza Abbasgholizadeh, Jun Zhao, Guangchao Liu, Ruiqi Wang, Hongli Tang, Ryan Sun, Xiaoping Su, Tse-Hua Tan, Anirban Maitra, Huamin Wang
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	American Society for Clinical Investigation 2023-06-01
الموضوعات:	Gastroenterology
الوصول للمادة أونلاين:	https://doi.org/10.1172/JCI163873