Influenza A(H1N1)pdm09 Virus with Reduced Susceptibility to Baloxavir, Japan, 2024

Influenza A(H1N1)pdm09 virus carrying an I38N substitution was detected in an untreated teenager in Japan. The I38N mutant virus exhibited reduced susceptibility to baloxavir but remained susceptible to neuraminidase inhibitors and showed reduced growth capability. Monitoring antiviral drug suscept...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Emerging Infectious Diseases
المؤلفون الرئيسيون:	Emi Takashita, Hiroko Morita, Shiho Nagata, Seiichiro Fujisaki, Hideka Miura, Tatsuya Ikeda, Kenichi Komabayashi, Mika Sasaki, Yohei Matoba, Tomoko Takahashi, Naomi Ogawa, Katsumi Mizuta, Sueshi Ito, Noriko Kishida, Kazuya Nakamura, Masayuki Shirakura, Shinji Watanabe, Hideki Hasegawa
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Centers for Disease Control and Prevention 2025-05-01
الموضوعات:	influenza virus influenza viruses cap-dependent endonuclease inhibitor baloxavir marboxil baloxavir acid
الوصول للمادة أونلاين:	https://wwwnc.cdc.gov/eid/article/31/5/24-1123_article