Efficacy of 5-hydroxytryptamine 3 receptor antagonists versus metoclopramide for preventing nausea and vomiting during azacitidine chemotherapy in patients with myelodysplastic syndromes or acute leukemia: a retrospective observational study

Abstract Background 5-Hydroxytryptamine 3 receptor antagonists (5-HT3RAs) and dexamethasone are recommended to prevent azacitidine-induced nausea and vomiting. In clinical practice, 5-HT3RAs or metoclopramide is often used without dexamethasone. In this study, we aimed to determine whether 5-HT3RAs...

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Bibliographic Details
Published in:Journal of Pharmaceutical Health Care and Sciences
Main Authors: Yoshinori Wakasugi, Yoshito Ikeda, Satoshi Noda, Makoto Murata, Shin-ya Morita
Format: Article
Language:English
Published: BMC 2025-04-01
Subjects:
Ramosetron
Granisetron
Metoclopramide
Azacitidine
Nausea
Vomiting
Online Access:https://doi.org/10.1186/s40780-025-00444-3

Internet

https://doi.org/10.1186/s40780-025-00444-3

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