Functional characterization of goose IRF1 in IFN induction and anti-NDV infection

Abstract Interferon regulatory factors (IRFs) play a key role in many aspects of immune response, and IRF1, IRF3, and IRF7 are positive regulators of IFN induction in mammals. However, IRF3, as the most critical regulatory factor in mammals, is naturally absent in birds, which attracts us to study t...

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Bibliographic Details

Published in:	Veterinary Research
Main Authors:	Zhenyu Lin, Jie Wang, Nian Zhang, Jianshu Yi, Zhaofei Wang, Jingjiao Ma, Hengan Wang, Yaxian Yan, Kun Qian, Jianhe Sun, Yuqiang Cheng
Format:	Article
Language:	English
Published:	BMC 2022-04-01
Subjects:	Goose IRF1 IFN innate immunity NDV
Online Access:	https://doi.org/10.1186/s13567-022-01046-9