Trypanosoma brucei Co-opts NK Cells to Kill Splenic B2 B Cells.
After infection with T. brucei AnTat 1.1, C57BL/6 mice lost splenic B2 B cells and lymphoid follicles, developed poor parasite-specific antibody responses, lost weight, became anemic and died with fulminating parasitemia within 35 days. In contrast, infected C57BL/6 mice lacking the cytotoxic granul...
| Published in: | PLoS Pathogens |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2016-07-01
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| Online Access: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1005733&type=printable |