An in vitro model for Lewy body-like hyaline inclusion/astrocytic hyaline inclusion: induction by ER stress with an ALS-linked SOD1 mutation.

Neuronal Lewy body-like hyaline inclusions (LBHI) and astrocytic hyaline inclusions (Ast-HI) containing mutant Cu/Zn superoxide dismutase 1 (SOD1) are morphological hallmarks of familial amyotrophic lateral sclerosis (FALS) associated with mutant SOD1. However, the mechanisms by which mutant SOD1 co...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Satoru Yamagishi, Yoshihisa Koyama, Taiichi Katayama, Manabu Taniguchi, Junichi Hitomi, Masaaki Kato, Masashi Aoki, Yasuto Itoyama, Shinsuke Kato, Masaya Tohyama
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2007-10-01
Online Access:	http://europepmc.org/articles/PMC2000355?pdf=render