Transmembrane topology and oligomeric nature of an astrocytic membrane protein, MLC1

MLC1 is a membrane protein mainly expressed in astrocytes, and genetic mutations lead to the development of a leukodystrophy, megalencephalic leukoencephalopathy with subcortical cysts disease. Currently, the biochemical properties of the MLC1 protein are largely unknown. In this study, we aimed to...

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Bibliographic Details
Published in:Open Biology
Main Authors: Junmo Hwang, Kunwoong Park, Ga-Young Lee, Bo Young Yoon, Hyunmin Kim, Sung Hoon Roh, Byoung-Cheol Lee, Kipom Kim, Hyun-Ho Lim
Format: Article
Language:English
Published: The Royal Society 2021-12-01
Subjects:
MLC1
membrane protein
transmembrane topology
subunit stoichiometry
fluorescence quenching
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.210103

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https://royalsocietypublishing.org/doi/10.1098/rsob.210103

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