A Toxoplasma gondii O-glycosyltransferase that modulates bradyzoite cyst wall rigidity is distinct from host homologues

Abstract Infection with the apicomplexan protozoan Toxoplasma gondii can be life-threatening in immunocompromised hosts. Transmission frequently occurs through the oral ingestion of T. gondii bradyzoite cysts, which transition to tachyzoites, disseminate, and then form cysts containing bradyzoites i...

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Bibliographic Details
Published in:Nature Communications
Main Authors: Pranav Kumar, Tadakimi Tomita, Thomas A. Gerken, Collin J. Ballard, Yong Sok Lee, Louis M. Weiss, Nadine L. Samara
Format: Article
Language:English
Published: Nature Portfolio 2024-05-01
Online Access:https://doi.org/10.1038/s41467-024-48253-w