Shikonin from lithospermum erythrorhizon induces pyroptosis in trophoblast cells by activating the CTSB-NLRP3 inflammasome

Background With the decline of global fertility, drug therapeutic of ectopic pregnancy is of great significance. Lithospermum erythrorhizon is using for embryo killing as herbal medicine. Shikonin is the critical nucleus of Lithospermum erythrorhizon; however, the mechanism is still unclear. The stu...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Annals of Medicine
المؤلفون الرئيسيون: Fuling Zeng, Yuling Lai, Yanxi Huang, Fangfang Zhu, Jie Gao, Zhenyue Chen, Lihua Zeng, Min Feng, Pin Qiu, Shuo Yuan, Gaopi Deng
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Taylor & Francis Group 2024-12-01
الموضوعات:
Shikonin
network pharmacology
cathepsin B
NLRP3 inflammasome
pyroptosis
الوصول للمادة أونلاين:https://www.tandfonline.com/doi/10.1080/07853890.2024.2394584

الانترنت

https://www.tandfonline.com/doi/10.1080/07853890.2024.2394584

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