Gold nanoparticle distribution in advanced in vitro and ex vivo human placental barrier models

Abstract Background Gold nanoparticles (AuNPs) are promising candidates to design the next generation NP-based drug formulations specifically treating maternal, fetal or placental complications with reduced side effects. Profound knowledge on AuNP distribution and effects at the human placental barr...

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Bibliographic Details

Published in:	Journal of Nanobiotechnology
Main Authors:	Leonie Aengenheister, Dörthe Dietrich, Amin Sadeghpour, Pius Manser, Liliane Diener, Adrian Wichser, Uwe Karst, Peter Wick, Tina Buerki-Thurnherr
Format:	Article
Language:	English
Published:	BMC 2018-10-01
Subjects:	Gold nanoparticle Placental uptake and translocation Ex vivo placenta perfusion Placental in vitro co-culture model Nanoparticle agglomeration
Online Access:	http://link.springer.com/article/10.1186/s12951-018-0406-6