Direct and accurate miRNA detection based on CRISPR/Cas13a-triggered exonuclease-iii-assisted colorimetric assay

Abstract The abnormally expressed microRNAs (miRNAs) serve as crucial indicators for disease diagnosis and are strongly associated with the progression of various diseases. The quantification of miRNAs is highly significant for the clinical diagnosis and treatment of various types of cancers. This s...

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Bibliographic Details

Published in:	Journal of Analytical Science and Technology
Main Authors:	Yunxiao Li, Qiuxia Wang, Yali Wang
Format:	Article
Language:	English
Published:	SpringerOpen 2024-04-01
Subjects:	microRNAs (miRNAs) Exonuclease-iii (Exo-iii) Clustered regularly interspaced short palindromic repeats (CRISPR) Color reaction
Online Access:	https://doi.org/10.1186/s40543-024-00434-4