The impact of tumor associated macrophages on tumor biology under the lens of mathematical modelling: A review

In this article, we review the role of mathematical modelling to elucidate the impact of tumor-associated macrophages (TAMs) in tumor progression and therapy design. We first outline the biology of TAMs, and its current application in tumor therapies, and their experimental methods that provide insi...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Pejman Shojaee, Federica Mornata, Andreas Deutsch, Massimo Locati, Haralampos Hatzikirou
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-11-01
Subjects:	tumor-associated macrophage (TAM) tumor-macrophage interactions tumor microenvironment (TME) mathematical modelling cancer immunotherapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.1050067/full