Oxygen-linked S-nitrosation in fish myoglobins: a cysteine-specific tertiary allosteric effect.

The discovery that cysteine (Cys) S-nitrosation of trout myoglobin (Mb) increases heme O2 affinity has revealed a novel allosteric effect that may promote hypoxia-induced nitric oxide (NO) delivery in the trout heart and improve myocardial efficiency. To better understand this allosteric effect, we...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Signe Helbo, Andrew J Gow, Amna Jamil, Barry D Howes, Giulietta Smulevich, Angela Fago
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Online Access:	http://europepmc.org/articles/PMC4039430?pdf=render