Molecular Features and Metal Ions That Influence 10-23 DNAzyme Activity
Deoxyribozymes (DNAzymes) with RNA hydrolysis activity have a tremendous potential as gene suppression agents for therapeutic applications. The most extensively studied representative is the 10-23 DNAzyme consisting of a catalytic loop and two substrate binding arms that can be designed to bind and...
| Published in: | Molecules |
|---|---|
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-07-01
|
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/25/13/3100 |