TIPred: a novel stacked ensemble approach for the accelerated discovery of tyrosinase inhibitory peptides

Abstract Background Tyrosinase is an enzyme involved in melanin production in the skin. Several hyperpigmentation disorders involve the overproduction of melanin and instability of tyrosinase activity resulting in darker, discolored patches on the skin. Therefore, discovering tyrosinase inhibitory p...

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Bibliographic Details

Published in:	BMC Bioinformatics
Main Authors:	Phasit Charoenkwan, Sasikarn Kongsompong, Nalini Schaduangrat, Pramote Chumnanpuen, Watshara Shoombuatong
Format:	Article
Language:	English
Published:	BMC 2023-09-01
Subjects:	Tyrosinase inhibitory peptides Sequence analysis Bioinformatics Machine learning Feature selection Stacking strategy
Online Access:	https://doi.org/10.1186/s12859-023-05463-1