Characterization of diseased primary human hepatocytes in an all-human cell-based triculture system

Abstract Liver diseases, including NAFLD, are a growing worldwide health concern. Currently, there is a lack of suitable in vitro models that sustain basic primary human hepatocyte (PHH) morphology and functionality while supporting presentation of disease-associated phenotypic characteristics such...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Justin J. Odanga, Sharon M. Anderson, Erick K. Breathwaite, Sharon C. Presnell, Edward L. LeCluyse, Jingsong Chen, Jessica R. Weaver
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-03-01
Subjects:	Liver Hepatocytes Human Disease NASH
Online Access:	https://doi.org/10.1038/s41598-024-57463-7