USP2 reversed cisplatin resistance through p53-mediated ferroptosis in NSCLC

Abstract Background It has demonstrated the indispensable role of ferroptosis in conferring cisplatin resistance in non-small cell lung cancer (NSCLC), as well as the involvement of ubiquitin-specific protease (USP) in regulating ferroptosis. This paper aspired to the mechanism of USP2 and ferroptos...

Full description

Bibliographic Details
Published in:BMC Medical Genomics
Main Authors: Yanmei Gong, Ruichao Li, Rui Zhang, Li Jia
Format: Article
Language:English
Published: BMC 2025-02-01
Subjects:
USP2
p53
Cisplatin resistance
Ferroptosis
Online Access:https://doi.org/10.1186/s12920-025-02108-5

Internet

https://doi.org/10.1186/s12920-025-02108-5

Similar Items