Drastic transformation of visceral adipose tissue and peripheral CD4 T cells in obesity

Obesity has a pronounced effect on the immune response in systemic organs that results in not only insulin resistance but also altered immune responses to infectious diseases and malignant tumors. Obesity-associated microenvironmental changes alter transcriptional expression and metabolism in T cell...

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Bibliographic Details
Published in:Frontiers in Immunology
Main Authors: Kohsuke Shirakawa, Motoaki Sano
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1044737/full