The role of PAR2 in regulating MIF release in house dust mite-induced atopic dermatitis

Atopic dermatitis (AD) is a chronic disease characterized by relapsed eczema and intractable itch, and is often triggered by house dust mites (HDM). PAR2 is a G-protein coupled receptor on keratinocytes and may be activated by HDM to affect AD processes. We first established a HDM-derived AD mouse m...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Lingxuan Zhou, Guohong Zhang, Kai Zhang, Ziyan Rao, Zhanli Tang, Yang Wang, Jiahui Zhao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-10-01
Subjects:	atopic dermatitis house dust mite PAR2 MIF release single-cell transcriptomics
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1478292/full