MicroRNA-505, Suppressed by Oncogenic Long Non-coding RNA LINC01448, Acts as a Novel Suppressor of Glycolysis and Tumor Progression Through Inhibiting HK2 Expression in Pancreatic Cancer

Background: MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) play vital regulatory roles in pancreatic cancer (PC) initiation and progression. We aimed to explore the biological functions and underlying mechanisms of miR-505-3p (miR-505) in PC.Methods: We first screened miRNA expression profile...

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Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Zhenglei Xu, Dingguo Zhang, Zhuliang Zhang, Weixiang Luo, Ruiyue Shi, Jun Yao, Defeng Li, Lisheng Wang, Bihong Liao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-01-01
Subjects:	long non-coding RNA microRNA miR-505 HK2 pancreatic cancer
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2020.625056/full