Development of neoantigens: from identification in cancer cells to application in cancer vaccines

ABSTRACTIntroduction The discovery of neoantigens as mutated proteins specifically expressed in tumor cells but not in normal cells has led to improved cancer vaccines. Targeting neoantigens can induce anti-tumor T-cell responses to destroy tumors without damaging healthy cells. Extensive advances i...

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Bibliographic Details

Published in:	Expert Review of Vaccines
Main Authors:	Nasim Ebrahimi, Maryam Akbari, Masoud Ghanaatian, Parichehr Roozbahani moghaddam, Samaneh Adelian, Marziyeh Borjian Boroujeni, Elnaz Yazdani, Amirhossein Ahmadi, Michael R. Hamblin
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2022-07-01
Subjects:	Anti-cancer vaccines cancer immunotherapy neoantigens personalized vaccines t cell responses
Online Access:	https://www.tandfonline.com/doi/10.1080/14760584.2021.1951246