Pharmacogenomics of intravenous immunoglobulin response in Kawasaki disease

IntroductionKawasaki disease (KD) is a diffuse vasculitis in children. Response to high dose intravenous gamma globulin (IVIG), the primary treatment, varies according to genetic background. We sought to identify genetic loci, which associate with treatment response using whole genome sequencing (WG...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Sadeep Shrestha, Howard W. Wiener, Hidemi Kajimoto, Vinodh Srinivasasainagendra, Dolena Ledee, Sabrina Chowdhury, Jinhong Cui, Jake Y. Chen, Mikayla A Beckley, Luz A. Padilla, Nagib Dahdah, Hemant K. Tiwari, Michael A. Portman
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-01-01
Subjects:	Kawasaki disease whole genome sequencing IVIG refractory ancestry Pharmacaeconomics
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1287094/full