Tlr7 drives sex- and tissue-dependent effects in Sjögren’s disease

Primary Sjögren’s disease (pSD) is a systemic autoimmune disease that has the strongest female predilection of all autoimmune diseases. The underlying mechanisms that govern this sexual dimorphism, however, remain poorly understood. We hypothesized that pSD females would exhibit more robust disease...

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Bibliographic Details
Published in:Frontiers in Cell and Developmental Biology
Main Authors: Achamaporn Punnanitinont, Sheta Biswas, Eileen M. Kasperek, Jason Osinski, Chengsong Zhu, Jeffrey C. Miecznikowski, Rose-Anne Romano, Jill M. Kramer
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-09-01
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Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1434269/full