Epigenetic Changes Regulating Epithelial–Mesenchymal Plasticity in Human Trophoblast Differentiation

The phenotype of human placental extravillous trophoblast (EVT) at the end of pregnancy reflects both differentiation from villous cytotrophoblast (CTB) and later gestational changes, including loss of proliferative and invasive capacity. Invasion abnormalities are central to major obstetric patholo...

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Bibliographic Details

Published in:	Cells
Main Authors:	William E. Ackerman IV, Mauricio M. Rigo, Sonia C. DaSilva-Arnold, Catherine Do, Mariam Tariq, Martha Salas, Angelica Castano, Stacy Zamudio, Benjamin Tycko, Nicholas P. Illsley
Format:	Article
Language:	English
Published:	MDPI AG 2025-06-01
Subjects:	trophoblast differentiation epithelial–mesenchymal transition DNA methylation
Online Access:	https://www.mdpi.com/2073-4409/14/13/970