Nephroprotective Effects of Cilastatin in People at Risk of Acute Kidney Injury: A Systematic Review and Meta-analysis

Rationale & Objective: Cilastatin is an inhibitor of drug metabolism in the proximal tubule that demonstrates nephroprotective effects in animals. It has been used in humans in combination with the antibiotic imipenem to block imipenem’s renal metabolism. This systematic review and meta-anal...

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Bibliographic Details

Published in:	Kidney Medicine
Main Authors:	Dilaram Acharya, Fanar Ghanim, Tyrone G. Harrison, Tayler Dawn Scory, Nusrat Shommu, Paul E. Ronksley, Meghan J. Elliott, David Collister, Neesh Pannu, Matthew T. James
Format:	Article
Language:	English
Published:	Elsevier 2024-12-01
Subjects:	Kidney failure nephroprotective drugs nephrotoxicity renal disease
Online Access:	http://www.sciencedirect.com/science/article/pii/S2590059524001249